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Urolithin A

Category: Featured Products

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What is Urolithin A?

In essence, it functions as a "gold-standard cleaner" within cells, facilitating the removal of aged and damaged mitochondria while recycling valuable components, thereby enabling cells to maintain a "youthful state" consistently.

Why is Urolithin A considered "reliable"?

The "sense of security" of urolithin A comes from:
Natural source: It is a metabolic product of foods such as pomegranates and strawberries. When we consume these foods every day, we are actually taking in (about 10-50mg) of it.
Authoritative certification: In 2018, it was listed by the US FDA as a "generally recognized as safe" substance. During clinical trials, no abnormal liver or kidney conditions were found even when 1000mg was consumed daily.

What is the APPLICATION of Urolithin A?

The key role of urolithin A is to initiate "mitochondrial autophagy" (replacing the mitochondria), and it has two "cleansing routes".
Route 1 (requiring "helpers"): By activating the two proteins PINK1 and Parkin, "label" the damaged mitochondria so that the cells can recognize them and remove them;
Route 2 (Direct Activation): Cause the receptor proteins such as BNIP3 to gather on the surface of the mitochondria, thereby directly initiating the cleaning process.

Urolithin A adds a "protective layer" to the cells, defending them from the effects of aging from the inside out.
Antioxidation: Activates the Nrf2 pathway, allowing cells to synthesize more "antioxidants" on their own, thereby reducing damage from free radicals;
Anti-inflammatory: Inhibits the NF-κB pathway and the release of inflammatory factors, thereby reducing the "chronic inflammation" state of the body at its source.

Ursolic acid can "calibrate" the biological clock. It can reverse the rhythm disorder of clock genes and tight junction proteins caused by inflammation by regulating the expression rhythm of core clock genes in intestinal epithelial cells.

Animal experiments have shown that urolithin A can increase the NAD+ level in mice by 50%, which is equivalent to the effect of a 5-fold dose of NR (a common NAD+ supplement).
Finally, not only urolithin A, there are many components and methods that can activate autophagy in cells. For instance, substances like spermidine, resveratrol, curcumin found in beans, grapes, and turmeric, as well as intermittent fasting and regular exercise, although they have different pathways, can all promote cells to remove damaged components and update functions, helping to delay aging. However, they should be carried out scientifically and moderately based on one's own situation.

Specifications

Item	Specification
Appearance	Beige to yellow powder
Identification	1 HNMR confirms to structure
LCMS	LCMS Conforms to MW
Water	≤0.5%
Purity (HPLC)	≥98.0%
Heavy metals
Pb	≤0.5ppm
As	≤1.5ppm
Cd	≤0.5ppm
Hg	≤0. 1ppm
Residual solvents
Methanol	≤3000ppm
TBME	≤1000ppm
Toluene	≤890ppm
DMSO	≤5000ppm
Acetic Acid	≤5000ppm
Conclusion	This product conforms to the specifications.
Storage	Store in a well-closed and dry place with room temperature and no direct sun light.

BN Q & A

Q: How can I obtain samples of BN's products?

A: To request samples for testing, please contact our sales team. We will guide you through the process to ensure you receive the samples you need.

Q: What certificates and documentation does BN provide with its products?

A: We provide essential certificates, including Certificates of Analysis (COA), safety data sheets (SDS), and technical data sheets (TDS), to ensure product quality and compliance.

Q: What is the MOQ (Minimum Order Quantity) for BN products?

A: BN sets MOQs to ensure cost-effective production and efficient inventory management. The exact MOQ depends on the specific product package and can be discussed with our sales team to meet your business needs.

Q: What warehousing services does BN offer?

A: BN has high-standard warehousing facilities equipped for efficient inventory management. We ensure strict control over product quality and expiration dates through regular inventory checks and monitoring. Our warehouse are located in California,Florida.

Q: Do you provide door-to-door delivery services?

A: Yes, we offer door-to-door delivery services, ensuring that your products are picked up from our facility and delivered directly to your specified location. This service simplifies logistics and enhances convenience for our clients .

Q: How does BN ensure the safety and quality of its products during storage and delivery?

A: We adhere to strict quality control measures in our warehousing, including temperature control and regular inspections. Our delivery services also include tracking options to monitor the safety and status of your shipments.

Q: Can I get additional documentation for regulatory approvals in my country?

A: Yes, we can provide the necessary documentation and support to assist with regulatory approvals, ensuring compliance with local regulations.

For any further inquiries or specific requests, feel free to reach out to our customer service team. We are here to assist you!

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